Psilocybin Research

The current state of clinical study into psilocybin.

What it is

Psilocybin is the primary psychoactive compound in certain mushroom species and the subject of active clinical research.

Community experience

Interest in what supervised, clinical settings have found for depression, end-of-life distress and substance use.

Community experience

Studied outcomes include reductions in depressive symptoms in trial populations.

Current evidence

Promising early trials in controlled clinical settings, with small sample sizes and unresolved questions about durability.

Current evidence

Trial conditions differ enormously from unsupervised use.

Psychological distress, destabilisation for people with certain psychiatric histories, medication interactions, and legal exposure.

This page is educational. It is not a protocol, a dose recommendation, or a suggestion to obtain any controlled substance.

Psychedelic-assisted therapy, clinical research and retreats are not the same thing

Four very different settings that get collapsed into one phrase.

I explored meditation for two years before anything else

Sam 34yo, Software engineer

“Everyone wanted to talk about mushrooms. I wanted to know what my own mind did when nothing was added to it.”